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Background Echo and nuclear studies have shown that coronary flow changes with the cold pressor test (CPT). CPT has been used to measure coronary flow response because it provides an endothelium-dependent coronary vasodilation that is sensitive for detecting early changes in coronary endothelial function. There was also a study showed myocardial perfusion increases during CPT with first pass perfusion imaging [1]. We studied the regional myocardial perfusion values in normal volunteers under stress (CPT), at rest, and myocardial flow reserve (MFR).

Preliminary quantitative myocardial perfusion in response to cold pressor test in normals