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Summary Cardiac magnetic resonance (CMR) is increasingly applied as the first line investigation into the causes of myocardial dysfunction and remodelling. Although regional fibrosis is easily imaged on late gadolinium enhancement, characterisation of myocardial conditions with diffuse fibrosis remains challenging. Several studies proposed T1 mapping of gadolinium-enhanced myocardium supported by an inverse relationship between T1 relaxation times and amount of fibrotic tissue on histology. We performed high-resolution modified LookLocker inversion recovery (hrMOLLI) imaging of native and postcontast myocardium in thirty-six subjects who underwent a routine CMR protocol for investigation of cardiomyopathy.

journal of cardiovascular magnetic resonance

Application of high resolution T1 mapping with MOLLI (hrMOLLI) to differentiate patients with diffuse and regional myocardial disease from healthy subjects