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Objective To evaluate MRI strain analysis for the assessment of myocardial function following stem cell therapy. Background MRI strain analysis is a novel way to assess myocardial function and may detect subtle improvements in myocardial function earlier than commonly used methods of myocardial function assessment. Stem cell therapy offers a promising approach to the regeneration of damaged vascular and cardiac tissue after myocardial infarction. Myocardial strain imaging has not been evaluated as an end point in stem cell studies. Our objective was to demonstrate the role and feasibility of MRI strain analysis for the early detection of myocardial functional improvement following stem cell therapy. Methods

MRI strain analysis as a novel modality for the assessment of myocardial function following stem cell therapy-results from Amorcyte trial