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Methods 22 patients with known or suspected CAD underwent both N-Ammonia PET and CMR adenosine stress and rest perfusion imaging prior to diagnostic coronary Xray angiography (CXA). CMR perfusion imaging was performed at 1.5T with a kt-accelerated steady-state free-precession sequence. Data analysis was blind. A significant coronary artery stenosis was defined as at least 70% diameter reduction or a fractional flow reserve <0.8. Sensitivity and specificity for PET and CMR versus invasive angiography were calculated. Localization of ischaemia was assessed in patients with CAD by classifying territories that were ischaemic on imaging as either supplied by, or as remote from, a stenotic artery.

Comparison of cardiac magnetic resonance imaging and positron emission tomography for the diagnosis and localization of coronary artery disease