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Objective To explore the suppression efficiency of spectrally selective fat suppression schemes when different black blood imaging pre-pulses are used. Background Sufficient peri-vascular fat suppression is critical for the outer wall boundary delineation in vessel wall imaging. The MSDE technique has been shown to significantly improve the blood suppression efficiency and measurement reproducibility. A limitation is that, due to the uncompensated eddy currents, undesired frequency shift can be observed after the MSDE prepulse, making the spectrally selective fat suppression ineffective. The aim of this study is to explore whether a previously proposed improved MSDE (iMSDE) technique is more robust against this system imperfection than the conventional MSDE approach, thus improving the fat suppression efficiency in vivo. Methods

iMSDE improves the fat suppression efficiency in vessel wall imaging