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Cardiovascular Magnetic Resonance CMR has provided the opportunity to quantify right ventricular (RV) parameters with excellent reproducibility and accuracy. The role of the RV is gaining ground in thalassemia major (TM) patients and this population could experience different “normal” RV values due to chronic anemia and eventually pre-existing iron burdens. In literature, there are no data on the ranges for “normal” RV volumes and ejection fraction (EF) in TM patients. The aim of this study was to establish the ranges for normal RV volumes, mass and ejection fraction normalized to the influence of body surface area (BSA), age and sex from CMR in a large cohort of well-treated TM patients without myocardial iron overload.

journal of cardiovascular magnetic resonance

Right Ventricular Volumes and Function normalized to body surface area, age and sex in a large cohort of well-treated Thalassemia Major without myocardial iron overload