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Background Late gadolinium enhancement (LGE) in cardiac MRI (cMRI) has been described as a valid tool to discriminate between cardiac diseases. It has been postulated that MLE especially occurs in patients with dilated cardiomyopathy (DCM) and myocarditis with a prognostic impact in these patients. Nevertheless, it can be difficult to differentiate true MLE from common artifacts as motion blur, partial volume effects (PVE) or wrong inversion times (TI), especially for the IO.

Frequency and variability of late gadolinium "mid-wall" enhancement(MLE) depending on observer experience, image quality and underlying disease