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The uptake of gadolinium contrast agent in coronary walls may indicate metabolically-active atherosclerosis (Maintz et al, 2006 ) and therefore be useful in the setting of coronary allograft vasculopathy (CAV). The interpretation of inversion recovery (IR) images can be hampered by signal from tissues with longer T1 times (particularly the myocardium) as tissue suppression is T1 dependent and only optimal for one specific T1 species (e.g. blood). We sought to improve contrast-enhanced coronary vessel wall imaging using a novel non-selective double inversion recovery (NS-DIR) prepulse that provides signal suppression over a wide user-defined T1-range.

Post-contrast non-selective double inversion recovery imaging of the coronary arteries in patients with coronary allograft vasculopathy