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Background Late gadolinium enhancement (LGE) with infarct tissue heterogeneity characterized by cardiac magnetic resonance imaging (CMR) has been shown to be associated with arrhythmogenic substrates and increased mortality. Preliminary data suggests that areas of heterogeneous signal intensity (SI) within an infarct may represent an admixture of myocardial fibrosis, ischemic cellular apoptosis and viable myocytes potentially capable of functional recovery.

journal of cardiovascular magnetic resonance

Serial quantification of myocardial infarction tissue heterogeneity during infarct healing by cardiac MRI provides strong characterization of left ventricular remodeling (the NHLBI PROSPECT-CMR Study)