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Cardiac Resynchronization Therapy (CRT) has been shown to improve quality of life and decrease mortality in heart failure patients. However, up to 40% of patients fail to respond to this therapy. Validation of a response prediction model that incorporates both myocardial scar and dyssynchrony of the paced myocardial segments would allow for a targeted approach to CRT lead delivery.

journal of cardiovascular magnetic resonance

Paced segment characteristics predict clinical response to cardiac resynchronization therapy: results from the multimodality imaging assessment of pacing intervention in heart failure (MAPIT-HF) study