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Background Autopsy studies [1,2] and x-ray CT in older subjects with suspected disease [3] have demonstrated increasing coronary vessel thickness with age. There is, however, a need for a radiation-free non-invasive technique for use in longitudinal studies of coronary vessel wall morphology. Recently 3D MR coronary vessel wall imaging with retrospective beat-to-beat respiratorymotion-correction (B2B-RMC)[4], which uses 3D low resolution data acquired immediately before the main imaging data to retrospectively correct respiratory motion, has demonstrated great promise [5]. We propose that 3D high resolution MR with B2B-RMC can demonstrate coronary vessel wall thickening with age in healthy subjects.

MRI detects coronary vessel wall thickening with age in healthy subjects