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High spatial resolution imaging enables detailed assessments of the spatial variation of myocardial perfusion. Transmural gradients in myocardial perfusion are of particular interest, as the endocardium is more sensitive to ischaemia from a coronary stenosis than the epicardium. Gradients in myocardial perfusion are also seen in left ventricular hypertrophy and microvascular disease.

Visualization and characterization of transmural gradients in high resolution first pass perfusion images