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Results Peak oxygen uptake was strongly correlated to THV (r2 = 0.74, P < 0.001) in the control subjects, but not for the patients (r2 = 0.0006, p = 0.90). The cardiac reserve index differed significantly between control subjects and patients (Figure 1A), even in patients with normal ejection fraction and after normalizing for hemoglobin levels (P < 0.001, Figure 1B). In both figures, the box represents the median, the 25th and the 75th percentile and the whiskers represent minimum and maximum values. In a multivariate analysis the cardiac reserve index was the only independent predictor of presence of HF (P < 0.001).

journal of cardiovascular magnetic resonance

Cardiac reserve index as a novel method for diagnosing heart failure: a cardiac magnetic resonance study in heart failure patients, healthy volunteers and athletes