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Methods Between January 2003 and 2008, we prospectively included 16 patients with LVNC. During the mean period we included 16 patients with dilated cardiomyopathy (DCM), 16 patients with hypertrophic cardiomyopathy (HCM), and 16 control subjects. All patients underwent a 1.5 T CMR with SSFP cine sequences, the following parameters were used: TR/TE = 40 ms/1.8 ms, slice thickness = 6 mm, no gap between slice, flip angle = 65°, matrix = 148 × 256, field of view = 350 × 350 mm, temporal resolution = 35 ms, retrospective gating for the Siemens scan; and TR/TE = 3.5/1.5 ms, slice thickness = 6 mm, no gap between slice, flip angle = 60°, matrix = 148 × 256, field of view = 350 × 350 mm, temporal resolution = 35 ms, retrospective gating for the Philips scan. LV volumes, LV ejection fraction and trabeculated LV mass were measured (Figure 1). Figure 1: Illustration of the described method for measuring the global and trabeculated LV masses in patients with LVNC, DCM, HCM and controls. Row A shows the short axis end-diastolic cine images used for measurement without contouring. Row B shows inclusion of papillary muscles but exclusion of LV trabeculation for the measurements of the compacted LV mass. Row C shows inclusion of papillary muscles and trabeculation for the measurements of global LV mass.

New insight of CMR in the diagnosis of left ventricular non-compaction: measurement of trabeculated left ventricular mass