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Aortic compliance (AC) can be evaluated noninvasively and its reduction with age in normals has been demonstrated with both MRI and Doppler echo methods. Aortic pulse wave velocity (PWV), a measurement of the flow pulse traveling along aorta as a surrogate of AC, can be assessed using a single breath-hold phase contrast (PC) imaging technique. Accurate determination of the time delay (Δt) between flows in ascending and descending aortic regions is critical in PWV assessment.

Detection of time delay using cross-correlation for aortic pulse wave velocity evaluation