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In thalassemia patients the significant presence of myocardial fibrosis/necrosis seems to be a time dependent process correlating with cardiovascular risk factors and cardiac complications. HCV infection could be a causal agent in the pathogenesis of myocardial scarring. ECG changes showed a good accuracy in predicting myocardial scarring

Prevalence and clinical correlates of miocardial fibrosis and necrosis in thalassemia major patients by CMR-DE