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The quantification of myocardial perfusion using MRI is a sensitive method for detecting ischemia. The limitations of myocardial perfusion quantification include artifacts, sequence dependence, and saturation effects associated with high contrast agent concentration in the LV. The dual bolus method solves the blood signal saturation problem by using two contrast injections to acquire low contrast dose imaging of LV blood, followed by high contrast dose imaging of myocardium. The objective of this study was to determine whether the resting perfusion quantification using the dual bolus approach is dependent on the MRI pulse sequence or imaging plane orientation.

237 MRI myocardial perfusion quantification: effects from contrast dose, imaging plane and sequence