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Left ventricular ejection fraction (LVEF) is traditionally used as a clinical marker for prognosis and clinical risk stratification. Decisions for prescribing clinical therapies are frequently based on LVEF. The results from existing literature are conflicted with respect to the existence of a gender difference in LVEF. One explanation is that greatly varying magnetic resonance imaging techniques including SSFP, GRE, or hybrid echo planar cine methods were used or that small sample sizes were studied in the publications to date. Thus, it remains unclear whether statistically significant gender-specific differences between LVEF exist.

2083 Women have higher left ventricular ejection fractions than men: a multivariable analysis in 4864 subjects using SSFP cine MRI