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30 ± 8 ml/m2) and RVMI (22 ± 5 gr/m2 vs. 19 ± 4 gr/m2) and a lower RVEF (46 ± 7% v 52 ± 8%) compared to women <60 years old (n = 25). No statistical significant differences were found in the indexed right ventricular volumes, mass and function between men and women ≥ 60. In men, RVEDVI (71 ± 13 ml/m2 vs. 57 ± 14 ml/m2), RVESVI (38 ± 9 ml/m2 vs. 28 ± 6 ml/m2) and RVMI (22 ± 5 gr/m2 vs. 18 ± 3 gr/m2) decreased with age while RVEF (46 ± 7 ml/m2 vs. 51 ± 8%) and M/V ratio (0.38 ± 0.06 gr/ mlvs. 0.42 ± 0.07 gr/ml) increased but similar changes were not observed in women. In men, Pearson correlation analysis demonstrated an age related decrease in RVEDVI (r = -0.41, p < 0.05), RVESVI (r = -0.45, p < 0.05) and RVMI (r = -0.29, p < 0.05) while the M/V increased (r = 0.29, p < 0.05). Similar relationships were not observed in women. Conclusion These data suggest that ageing has a different impact on RV morphology in men and women. The mechanism responsible for the gender related changes are unclear.

2053 Age and sex related changes in right ventricular dimensions and systolic function