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Cardiac amyloidosis is the most common cause of restrictive cardiomyopathy, involving extracellular tissue deposition of various serum proteins. Up to 50% involve AL amyloid, its most severe form, which causes drastic cardiac dysfunction with a 38% 1 year-survival rate. Diagnosis of cardiac amyloidosis remains difficult outside endomyocardial biopsy. Cardiovascular magnetic resonance has been studied and used as a non-invasive method for diagnosis. The myocardium exhibits a diffuse late enhancement pattern as well as a shorter T1 after contrast administration (Circulation 111:168–193, 2005). We aim to describe a role for pre-contrast cardiac MRI in the evaluation of cardiac amyloidosis by evaluating its T1 signal using both quantitative and qualitative measures.

2034 Assessment of left ventricular myocardial T1 hyperintensity in patients with suspected cardiac amyloidosis using MRI