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Background Cardiovascular magnetic resonance (CMR) with delayed enhancement (DE) has become the gold standard for the identification and quantification of myocardial fibrosis in coronary artery disease. In this regard, DE thresholding to 2 standard deviations above normal myocardium is now considered the most robust method for quantifying fibrosis with high accuracy and reproducibility. However, whether this method is the most appropriate for nonischemic cardiomyopathies such as hypertrophic cardiomyopathy remains uncertain. Our goal was to compare the performance of various thresholding techniques to a visual assessment in a large cohort of patients with hypertrophic cardiomyopthy (HCM).

journal of cardiovascular magnetic resonance

2027 Accuracy and reproducibility of quantifying myocardial fibrosis in hypertrophic cardiomyopathy using delayed enhancement cardiovascular magnetic resonance thresholding techniques