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Bolus-chase magnetic resonance angiography (MRA) protocols covering the entire peripheral vasculature must be considered as the state of the art technique and imaging modality of first choice in patients suffering from peripheral arterial disease (PAD). However, even if technically perfect, standard MRA techniques only provide morphologic information whereas digital subtraction angiography as the standard of reference provides additional information on flow. To overcome these limitations at least for the infrapopliteal arteries hybrid MRA techniques combining time-resolved MRA of the lower legs and bolus chase MRA for the pelvis and upper legs have been introduced. The results of hybrid MRA are encouraging but until now spatial resolution is scarified in dynamic MRA to improve the temporal resolution. Additionally, dynamic information about arterial filling and venous enhancement is only available for in the infrapopliteal vessels. Therefore our study aimed to develop a triple injection scan protocol for dynamic, high-resolution, isotropic MRA of the entire peripheral vascular system applying a recently developed time-resolved 3D MRA sequence (TWIST).

1043 High spatial and temporal resolution MRA of the entire peripheral vascular system using a new 3D time-resolved MRA technique (TWIST)