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Introduction It is a known fact that utilizing the proper inversion time (TI) is essential in diagnosing myocardial infarctions. Many factors play a key role in acquiring optimal nulling of the myocardium. We have shown that the amount of gadolinium dosage administered plays a major role on TI. It has been shown that a low gadolinium dosage will yield a higher TI while a high dosage results in a lower TI. The current conditions relating to the intrinsic contraction factors of the heart and their contribution to TI are currently unknown. For instance, how fast are the wash in/wash out kinetics in a patient with a high heart rate and a low ejection fraction?

403 Do heart rate, ejection fraction, stroke volume and cardiac output play a key role in optimal myocardial nulling?