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Background Specific cell therapy with tolerogenic Dendritic Cells (tolDCs) loaded with autoantigens is a promising tool for the attenuation of pathogenic T cells in autoimmune diseases such as Multiple Sclerosis (MS). The aim of this study was to analyse the in vitro effect of tolerogenic bone marrow derived DCs (BM-DCs) loaded with Myelin Oligodendrocyte Glycoprotein (MOG) 40-55 peptide from C57BL/6 mice, on the specific proliferation of splenocytes of mice with EAE.

Tolerogenic dendritic cells in experimental autoimmune encephalomyelitis, specific tolerance induction?