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Background It is very important to explore the new strategies of prevention and treatment of Ischemic heart disease (IHD) in molecular level. Notch signaling pathways are very expedient in terms of the protection and recovery of myocardial when the heart muscle is impaired. It is also known that ROCKs are closely related to the apoptosis of cardiomyocytes. We infer that there are interactions between Notch signaling pathways and ROCKs on cell apoptosis in H9c2 cardiomyocytes model of H/R.

Effect of Notch signal pathway on H9c2 cardiomyocytes apoptosis induced by hypoxia/reoxygenation via ROCK2