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Background  Reconstruction of large scalp defects after tumor resection is a challenging problem. We aimed at putting an algorithm for reconstruction of those defects.    Methods  Forty-two patients with scalp malignancies were enrolled in this study. Tumors were resected to a 1 cm negative margin and defects were reconstructed according to their size and to patient general condition.    Results  No peri-operative mortality was encountered. Usage of free flaps was superior in cosmoses and function with an acceptable rate of complications.    Conclusion  for scalp defects wider than100 cm 2 , the best tool of reconstruction is free flaps. Pedicled distant flaps are reserved if free flaps are not feasible or failed. Split thickness skin grafts are cosmetically inferior and not suitable for recurrent and irradiated tumours and better reserved for patients who cannot tolerate major operations.

Can we put a simplified algorithm for reconstruction of large scalp defects following tumor resection?