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Results All manifested complete remission of symptoms after combination therapy with litium (plasma levels above 0.8 mEq/lt) plus 1–3 mg of risperidone daily. The two of them are still free of symptomatology during the maintainance period for 16 and 17 months respectively. The third patient, after several months during which she was free of symptomatology discontinued lithium against the psychiatrist's advise and received only 3 mg of Risperidone daily. For the next 18 months (until now) the patient is under risperiodone monotherapy and free of symptomatology.

Three case-reports on the use of risperidone in the long-term treatment of bipolar disorder