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Material and Methods Thirty-two IPD patients with major depression (IPD-D) were matched for age, sex, age of disease onset and duration of disease with 32 non-depressed IPD patients (IPDND). Depression was diagnosed using the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I). The Unified Parkinson's Disease Rating Scale (UPDRS) was completed during clinical examination. Motor function was evaluated using the sum of items scores related with tremor, rigidity, bradykinesia and axial impairment, as well as the motor UPDRS subscale score (UPDRSm).

The impact of depression and antidepressant treatment on motor function of patients with idiopathic Parkinson's disease