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BackgroundFamilial Hypercholesterolaemia (FHc) is a commoninherited disorder, leading to raised serum cholesterolevident from the first year of life. One in 500 people areaffected by the minor heterozygote form of this condi-tion, of which an estimated 85% are unidentified.National English guidelines,producedbyNICE,high-light the importance of cholesterol screening and FHcidentification in prevention of coronary heart disease[1,2]. However, evidence based approaches to supportguideline implementation are under developed. Theincorporation of computerised patient specific remindersis thought to have clinical utility in the identification ofpatients with genetic conditions but as yet not evaluatedin primary care for FHc.Materials and methodsIn order to develop computer based prompts are accepta-ble to general practitioners a focus group was held forgeneral practitioners from the Inner City Derby area, ofwhich the outcome would inform the design of a futurefeasibility study to assess the use and impact of suchreminders for FHc in clinical practice.ResultsGeneral practitioners were in favour of specific patientreminders for early identification of individuals at risk ofFHc. Emerging themes included brevity, clear and succinctstatements, explicit actions that linked specific screeningtests to specific diseases and the need to tailor differentGP clinical systems.ConclusionsClinicians need to be alert to the prevalence of FHc inclinical practice. Based on results from both the focusgroup and preliminary work, PSR’s were considered to bean overall effective method of early identification of FHcin general practice and therefore considered relevant inpre-trial work to inform substantive research in the earlyidentification of FHc in primary care.

Early identification of familial hypercholesterolaemia in general practice using patient-specific reminders: focus group with General Practitioners