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Purpose Resistance to cancer chemotherapy is a major problem. Herb-drug combinations can offer a new potential to overcome such resistance. To quantitatively assess chemosensitizing effects of herb-drug combinations (HDC), a new approach that takes into account both the chemosensitizing effect (CE) and “safety” considerations of the HDC is proposed and used in describing the cytotoxic activity of Tripterygium wilfordii-docetaxel (TW-Dtx) combination on prostate cancer cell lines.

bmc complementary and alternative medicine

P01.40. A new approach for quantifying chemosensitizing effects from herb-drug combinations: assessment of Tripterygium Wilfordii-Docetaxel in prostate cancer