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Purpose Fifty percent of adults with mild cognitive impairment (MCI) develop Alzheimer’s disease (AD) within 5 years. Preliminary data suggest that mindfulness-based stress reduction (MBSR) increases gray matter density of the hippocampus, which atrophies in AD. We studied the safety, feasibility, and impact of MBSR on brain function, memory, and quality of life (QOL) among adults with MCI.

P02.146. Mindfulness based stress reduction in adults with mild cognitive impairment: a pilot study using fMRI