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Methods 228 persons with non-specific cLBP recruited from primary care and the general community were randomized to 12 weekly 75-minute classes of either yoga or intensive stretching, or to a self-care book. Back-related function (Roland-Morris Disability Scale), symptoms (0-10 score) and psychological mediators (fear avoidance, body awareness, self-efficacy, psychological distress, perceived stress, positive affect) were assessed at baseline and 6, 12, and 26 weeks later by blinded interviewers. Physical function was assessed at baseline and 12 weeks and saliva samples were collected for cortisol and DHEA analyses at baseline, 6 and 12 weeks. Open-ended questions were asked about benefits of yoga and stretching. Statistical analyses for mediators were conducted using the framework of Baron and Kenney.

OA11.03. Mediators of the effects of yoga and stretching on chronic low back pain (cLBP) outcomes: results from the YES RCT