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Background  Older patients with newly diagnosed type 2 diabetes mellitus are less likely to receive antihyperglycaemic therapy compared to their younger counterparts. The purpose of this study was to assess the reasons of general practitioners (GPs) for not treating younger and older patients with newly diagnosed type 2 diabetes mellitus with antihyperglycaemic agents.    Methods  In a survey conducted between November 2009 and January 2010, 358 GPs from the United Kingdom selected reasons for not initiating antihyperglycaemic therapy in younger (< 65 years) and older (≥65 years) patients with newly diagnosed type 2 diabetes mellitus and untreated with any antihyperglycaemic agent for at least six months following diagnosis. Thirty-six potential reasons were classified into four major categories:  Mild hyperglycaemia ,  Factors related to antihyperglycaemic agents ,  Comorbidities and polypharmacy , and  Patient-related reasons . Reasons for non-treatment were compared between younger (n = 1, 023) and older (n = 1, 005) patients.    Results  Non-treatment reasons related to  Mild hyperglycaemia  were selected more often by GPs for both younger (88%) and older (86%) patients than those in other categories. For older patients,  Factors related to antihyperglycaemic agents  (46% vs. 38%) and  Comorbidities and polypharmacy  (33% vs. 19%), both including safety-related issues, were selected significantly (p < 0.001) more often by GPs. No between-group difference was observed for the  Patient-related reasons  category. The GP-reported HbA 1c  threshold for initiating antihyperglycaemic therapy was significantly (p < 0.001) lower for younger patients (mean ± standard deviation: 7.3% ± 0.7) compared to older patients (7.5% ± 0.9).    Conclusions  GPs selected reasons related to  Mild hyperglycaemia  for non-treatment of their untreated patients with newly diagnosed type 2 diabetes mellitus, despite nearly one-third of these patients having their most recent HbA 1c  value ≥7%. The findings further suggest that safety-related issues may influence the non-treatment of older patients with type 2 diabetes mellitus.

bmc endocrine disorders

Reasons given by general practitioners for non-treatment decisions in younger and older patients with newly diagnosed type 2 diabetes mellitus in the United Kingdom: a survey study