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Background In psoriatic arthritis (PsA), nail disease is intimately linked to the presence of DIP joint enthesitis and arthritis. Nail disease has been shown in clinical trials to respond to treatment with TNF inhibitors. We used high resolution MRI to assess whether improvements in psoriasis-related nail disease correlated to improvements in associated DIP joint enthesitis, osteitis and synovitis during TNF inhibitor therapy.

Imaging of psoriatic nail disease pre and post anti-TNF therapy shows persistent subclinical inflammation despite good clinical response