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Background  Although the general assumption is that patients with rheumatoid arthritis (RA) have decreased levels of physical activity, no review has addressed whether this assumption is correct.    Methods  Our objective was to systematically review the literature for physical activity levels and aerobic capacity (VO 2max ). in patients with (RA), compared to healthy controls and a reference population. Studies investigating physical activity, energy expenditure or aerobic capacity in patients with RA were included. Twelve studies met our inclusion criteria.    Results  In one study that used doubly labeled water, the gold standard measure, physical activity energy expenditure of patients with RA was significantly decreased. Five studies examined aerobic capacity. Contradictory evidence was found that patients with RA have lower VO 2max  than controls, but when compared to normative values, patients scored below the 10 th  percentile. In general, it appears that patients with RA spend more time in light and moderate activities and less in vigorous activities than controls.    Conclusion  Patients with RA appear to have significantly decreased energy expenditure, very low aerobic capacity compared to normative values and spend less time in vigorous activities than controls.

Are persons with rheumatoid arthritis deconditioned? A review of physical activity and aerobic capacity