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Background  The influence of the fractionalization of moderate- to vigorous- intensity physical activity (MVPA) throughout the week on the health of children is unknown. We compared cardiometabolic risk factors in physically active children who accumulated their weekly MVPA in different patterns.    Methods  We studied 745 participants aged 6–19 years. MVPA was measured using accelerometers over 7 days. Three groups were created:  Insufficiently Active,  <60 minutes/day of MVPA on average;  Infrequently Active,  ≥60 minutes/day of MVPA on average but exceeding the 60 minute target <5 days; and  Frequently Active,  ≥60 minutes/day MVPA on average and exceeding the 60 minute target ≥5 days. Percentile scores for 8 cardiometabolic risk factors were determined.    Results  The least favorable cardiometabolic risk factor profile was observed in the  Insufficiently Active  group. The  Frequently Active  group had more favorable (5–6 percentile unit difference) diastolic blood pressure, HDL-cholesterol, insulin resistance, and metabolic syndrome scores than the  Infrequently Active  group, although only the difference for insulin resistance was statistically significant (P < 0.05). These differences remained after controlling for the weekly volume of MVPA.    Conclusion  The fractionalization of MVPA throughout the week was associated with insulin resistance.

The fractionalization of physical activity throughout the week is associated with the cardiometabolic health of children and youth