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Background  Fungal mural endocarditis is a rare entity in which the antemortem diagnosis is seldom made. Seven cases of mural endocarditis caused by  Candida  spp. have been collected from literature and six of these patients died after treatment with amphotericin B.    Case presentation  We report a case of mural endocarditis diagnosed by transesophageal echocardiogram and positive blood cultures to  Candida parapsilosis . Because blood cultures continued to yield  C. parapsilosis  despite caspofungin monotherapy, treatment with voriconazole was added.    Conclusion  This is the first description of successful treatment of  C. parapsilosis  mural endocarditis with caspofungin and voriconazole.

Successful treatment of Candida parapsilosis mural endocarditis with combined caspofungin and voriconazole