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Background Recruitment of patients in an RCT is crucial to the success of the trial. The sample selection and sample size estimation is based on previously reported research studies. We conducted an RCT to assess the effectiveness of mobile text messaging in improving adherence to highly active anti retroviral therapy in an ART unit of a tertiary care hospital. The present study was aimed to examine the impact of recruitment process and sampling on the outcome of the trial.

Methodological lacunae in recruitment of HIV positive persons in randomized controlled trials