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Methods A large cross sectional Integrated Behavioral and Biological Assessment (IBBA) survey for clients of female sex workers (FSWs) in the three districts (Chennai, Madurai and Salem) of Tamil Nadu, South India was carried out by India AIDS initiative, the Avahan project. The survey collected information from 1217 clients of female sex workers between June and September 2009. The data set was geocoded using Google Earth, Kulldorff Space time Scan Statistics was used for detection of clusters among the clients of FSWs.

Cluster detection of HIV infection for clients of female sex workers in selected districts of Tamil Nadu, South India