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Background   Mycobacteirum wolinskyi  is a member of the  Mycobacterium smegmatis  group, which is less frequently found in clinical settings than other nontuberculous mycobacterium (NTM) species. However, its clinical significance has recently increased in opportunistic infections. This case is the first report of facial skin and soft tissue infection by  M. wolinskyi  complicating cosmetic procedures.    Case presentation  A 56-year-old Asian female patient with a history of receiving multiple facial cosmetic procedures over the preceding 2 years was admitted to our institution with swelling, local pain, and erythema on the right cheek.  Mycobacteirum fortuitum  complex isolated from a pus culture was identified as  M. wolinskyi  by  rpoB  sequencing. Metallic foreign bodies and abscess were detected by radiologic imaging. The pus was incised and drained. Treatment comprised clarithromycin (500 mg every 12 h), amikacin (200 mg every 8 h), and ciprofloxacin (400 mg every 6 h).    Conclusion  We report the first case of facial skin and soft tissue infection with  M. wolinskyi  after multiple cosmetic procedures of filler injection and laser lipolysis. Increased occurrence of NTM infection in nosocomial settings suggests the importance of appropriate treatment including culturing and  rpoB  gene sequencing when patients who have undergone cosmetic procedures display symptoms and signs of soft tissue infection indicative of NTM infection.

Facial skin and soft tissue infection caused by Mycobacterium wolinskyi associated with cosmetic procedures