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Background The extreme variability at the Killer cell Immunoglobulin like Receptor (KIR) expressed on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA) Class I appear to play a crucial role in the outcome against viral infection. The combination of HLA/KIR gene products either individually or collectively have been implicated in the control of HIV-1 in various populations. Objective of this immunogenetic case-control study is to determine the association between KIR3DS1 and HIV-1 asymptomatism.

Protective effect of KIR3DS1 in asymptomatic HIV-1 seroconverters towards AIDS