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Background  Functional gastrointestinal disorders (FGID) may occur following acute gastroenteritis. This long-term complication has previously not been described after infection with the non-invasive protozoan  Giardia lamblia . This study aims to characterize persistent abdominal symptoms elicited by  Giardia  infection according to Rome II criteria and symptoms scores.    Methods  Structured interview and questionnaires 12–30 months after the onset of  Giardia  infection, and at least 6 months after  Giardia  eradication, among 82 patients with persisting abdominal symptoms elicited by the  Giardia  infection. All had been evaluated to exclude other causes.    Results  We found that 66 (80.5%) of the 82 patients had symptoms consistent with irritable bowel syndrome (IBS) and 17 (24.3%) patients had functional dyspepsia (FD) according to Rome II criteria. IBS was sub classified into D-IBS (47.0%), A-IBS (45.5%) and C-IBS (7.6%). Bloating, diarrhoea and abdominal pain were reported to be most severe. Symptoms exacerbation related to specific foods were reported by 45 (57.7%) patients and to physical or mental stress by 34 (44.7%) patients.    Conclusion  In the presence of an IBS-subtype pattern consistent with post-infectious IBS (PI-IBS), and in the absence of any other plausible causes, we conclude that acute  Giardia  infection may elicit functional gastrointestinal diseases with food and stress related symptoms similar to FGID patients in general.

Development of functional gastrointestinal disorders after Giardia lambliainfection