English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Background   Helicobacter pylori  is one of the most common causes of bacterial infection in human beings. Studies have showed a high prevalence of  Helicobacter pylori  among people in low-income countries and colonization early in life. A monoclonal antigen test, performed on faeces, HpSA ® ImmunoCardSTAT, has a high sensitivity, specificity and accuracy and the faecal test can be performed in all ages, also in resource-limited settings. The main objective of this study was to determine the prevalence and factors associated with  Helicobacter pylori  colonization in apparently healthy children aged 0-12 years in urban Kampala, Uganda.    Method  We tested 427 apparently healthy children, age 0-12 years (211 males, 216 females), in a cross sectional survey for  Helicobacter pylori  colonization using HpSA  ® ImmunoCardSTAT. A short standardized interview with socio-demographic information and medical history was used to assess risk factors.    Results  The overall prevalence of  Helicobacter pylori  in the 427 children was 44.3% (189 out of 427). Early colonization was common, 28.7%, in children younger than 1 year of age. The age specific rates were 46.0% in children age 1- < 3 years, 51.7% in children age 3- < 6 years, 54.8% in children age 6- < 9 years and 40.0% in children age 9- < 12 years. There was a significant difference in prevalence by gender; female 38.5% versus male 49.8% and by type of housing; permanent house 38.5% versus semi-permanent house 48.6%. Congestive living and education level of the female caretaker showed a clear trend for a difference in prevalence. Factors independently associated with  Helicobacter pylori  colonization included: drugs taken last three months, using a pit latrine, sources of drinking water and wealth index.    Conclusion  The prevalence of  Helicobacter  pylori colonization among urban Ugandan children is high at an early age and increases with age. The impact of Helicobacter pylori colonization on children's health in Uganda needs to be further clarified.

Helicobacter pyloriin apparently healthy children aged 0-12 years in urban Kampala, Uganda: a community-based cross sectional survey