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Purpose Clonidine and brimonidine, two α2 agonists, have been shown to reduce intraocular pressure in glaucoma patients. Little is, however, known about the exact role of alpha receptors in the control of ocular blood flow in the posterior pole of the eye. Hence, we set out to investigate the effects of topical clonidine vs. topical brimonidine on choroidal blood flow and intraocular pressure during isometric exercise.

Effects of topical clonidine vs. brimonidine on choroidal blood flow and intraocular pressure during isometric exercise