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How the olfactory system encodes odor concentration is a comparatively underexplored and largely unresolved question. We have constructed a model of the early olfactory system which is capable of a fuzzy signaling of concentration, through glomerular competition resulting in inhibition of most mitral cells. Each mitral cell responds optimally to a narrow odor concentration range. Method Our model consists of three separate subsystems: an olfactory receptor neuron array, a glomerulus module with inhibitory competition between mitral cells, and a bulb model with mitral and granule cells. The bulb model is implemented in the neural simulator NEURON and its two cell types are both Hodgkin-Huxley type multicompartmental models adapted after Davison et al [1], whose original model is freely accessible through the ModelDB database [2]. We simulate 25 mitral and 100 granule cells. from Seventeenth Annual Computational Neuroscience Meeting: CNS*2008 Portland, OR, USA. 19–24 July 2008

Fuzzy interval representation of olfactory stimulus concentration in an olfactory glomerulus model