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Spike Timing Dependent Plasticity (STDP), where the modification of a synapse depends on the time difference between preand post-synaptic spikes, has been observed in various types of neurons. In general, the STDP window function of excitatory synapses has a causal shape; a causal firing order (where the pre-synaptic neuron fires before the post-synaptic neuron) induces LTP, and an anti-causal firing order induces LTD. In contrast, anti-causal STDP has been described in some inhibitory neurons [1].

Asymmetric STDP in excitatory-inhibitory coupled neurons: a self-stabilizing mechanism?