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Methods Using texture analysis, we analysed 104 lesions in 104 patients suspected for lung cancer with a positive CT correlate. The analysis was performed using TexRAD (developed by TexRAD Ltd. UK). Histology was our reference standard. Malignancy was present in 92 lesions. CTTA comprised a filtration-histogram technique where filtration extracted and enhanced features of different sizes (fine, medium, coarse – scales) followed by histogram analysis using mean (M), entropy (E), uniformity (U), total number of voxels and kurtosis (K) within the entire volume of the suspected lesion. The operator performing the CTTA was blinded to the histological results.

CT texture analysis of pulmonary lesions in patients suspected for lung cancer