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Background Recent experimental evidence points out a possible involvement of outer and inner retinal layers in hypersensitivity of migraine patients to light stimuli. To investigate the short-wavelength-sensitive (S) and the medium/longwavelength-sensitive (ML) cone photoreceptors of the visual pathways in migraine without aura (MO) patients between attacks and in healthy volunteers (HV) by using yellow-blue (Y-B) or red-blue (R-B) visual flicker stimuli.

O026. An abnormal transduction of the chromatic stimuli from the outer to the inner retinal layers may contribute to cause photophobia in migraine