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Background Single-pulse transcranial magnetic stimulation studies of motor cortex have the advantage of relying on an objective measure, the motor evoked potential (MEP) recorded in peripheral muscles, to non-invasively explore the cortical excitability. Previously, thresholds for MEP were found to be normal, increased or even reduced in migraine. In the present study, we investigated whether the level of cortical excitability changes with the distance from the last migraine attack could explain these inconsistent results.

O025. Excitability of the motor cortex in migraine changes with the distance from the last attack