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Background In Italy, the estimated cost of chronic migraine (CM) is around six billion euros per year (Agenas, 2011) considering the health costs, the loss in working productivity and quality of life. The efficacy of BT-A in the prophylactic treatment of CM has been demonstrated [1]. However, BT-A therapy is expensive and the limited health service resource may raise the question of the cost/benefit ratio. Ruggeri et al [1] carried out a study to provide an estimate of the incremental cost-effectiveness ratio of the treatment of CM with BT-A 2 . They compared the benefit as extrapolated from the PREEMPT data with those of a population of CM from the METEOR study, as well as with those of an actual population of CM from a district of Rome [1]. In the present study we compared actual costs and benefit in a CM population before and after BT-A treatment.

P053. An Italian study on the actual cost/benefit of onabotulinumtoxinA (BT-A) in chronic migraine: preliminary results